Agenda

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7:45-8:30 a.m.                Continental Breakfast

8:30-8:35 a.m.                 Welcome and Overview
                                           Richard Katz, M.D.
                                           Professor of Medicine, Director, Division of Cardiology and the 
                                           Cheney Cardiovascular Institute,
                                           The George Washington University School of Medicine

8:35-9:15 a.m.                 Morning Keynote Speaker: Genomics for Developing Biomarkers
                                           Andrew Plump, M.D., Ph.D. 
                                           Executive Director, Cardiovascular Disease Franchise, Merck & Co.

9:15-9:55 a.m.                 Identifying Targets for Therapy Via Genomic Strategies
                                           Timothy McCaffrey, Ph.D.
                                           Professor of Biochemistry and Director,
                                           McCormick Genomics Center,
                                           The George Washington University School of Medicine

9:55a.m.                           Break

10:05-10:55 a.m.            Genomics & Congestive Heart Failure
                                          
Michael R. Bristow, M.D., Ph.D.
                                           Professor of Medicine, Division of Cardiology,
                                           University of Colorado Health Sciences Center,
                                           Chairman and Chief Science and Medical Officer, ARCA Discovery

10:55-11:35 a.m.            Applications of Pharmacogenomics to Improve Cardiovascular Drug Safety
                                           Raymond L. Woosley, M.D., Ph.D.

                                           President and CEO, The Critical Path Institute       

11:35-11:50 a.m.            Panel Discussion 

12:15-1:45 p.m.               Luncheon – Continental Ballroom
                                           The Marvin Center
                                           The George Washington University
                                           Luncheon Keynote Speaker: Genomics & Coronary Artery Disease
                                           Elizabeth G. Nabel, M.D.
 
                                           Director, National Heart, Lung, and Blood Institute (NHLBI)

2:00-2:40 p.m.                Markersand Mediators of Atherosclerosis revealed by Genomic Analysis of Circulating Cells
                                           Paul Hwang M.D., Ph.D. 
                                           Principal Investigator, Cardiology Branch National Heart, Lung, and Blood Institute

2:40-3:20 p.m.                Gene Variants Predict Risk of CHD and Clinical Benefit from Statin Therapy
                                           James J. Devlin, Ph.D.
                                           Director, Cardiovascular Research, Celera

3:20 p.m.                          Break

3:40-4:20 p.m.                Genotypic and Phenotypic Markers of CAD
                                           Robert Roberts, M.D.
                                           President and CEO University of Ottawa Heart Institute                                                                 

4:20-4:50 p.m.               Pilot Process for Biomarker Qualification at the FDA 
                                          Federico Goodsaid, Ph.D.
                                          Genomics Group, Office of Clinical Pharmacology, Office of Translational Science,
                                          Center for Drug Evaluation & Research

4:50-5:00p.m.                 Panel Discussion